Authors: Lt Col (Dr) Nasir Uddin 01732901299,01733076600
Institution: BGB Hospital,Dhaka and Labaid Specialised Hospital, Dhaka
Inflammatory Breast Cancer (IBC) is a rare and highly aggressive form of breast cancer characterized by rapid onset, inflammatory changes in the breast, and a poor prognosis. Its management requires a multidisciplinary approach due to its aggressive nature and diagnostic challenges.
This prospective study included patients who presented with Inflammatory Breast Cancer at different hospital of Bangladesh.
The study revealed that IBC continues to pose significant diagnostic challenges, often leading to delayed treatment initiation. Among the studies, a total of N=39 patients were managed within the past two years, and the prognosis remained unfavorable. Physical examinations consistently identified signs of inflammation, with skin changes in 54% of cases and palpable masses in 85%. Hormone receptor status revealed 23% of patients with triple- negative breast cancer (TNBC), while 31% were HER2 positive. Molecular classification showed that 31% belonged to the Luminal type-A category, and 31% were HER2 positive.
Inflammatory Breast Cancer management underscores the critical need for early detection and a multidisciplinary approach. The aggressive nature of IBC, coupled with diagnostic uncertainties, highlights the importance of a high clinical suspicion. To improve patient outcomes, timely and comprehensive management by a multidisciplinary team is imperative. This study highlights the complexity of IBC and underscores the importance of early intervention and holistic patient care despite the challenges faced.